top of page
Search

Case 37

Jan 26

A 50-year-old male with a 6.7 cm thigh mass and here is the biopsy.



  1. What stains you would like to order?


IHC

  • Keratin

  • S100

  • SOX10

  • CD34

You can vote for more than one answer.


  1. The tumors are classically positive for S100 however, in this form it's negative, but the tumor is positive for SOX11. What's the molecular for this entity?

    A: FUS-CREB

    B: EWSR1-ERG

    C: BCOR rearrangement

    D: GLI rearrangement

    E: FUS-DDIT3


Answer

Xu S, Dong Y, Huo Z, Yu L, Xue J, Wang G, Duan Y. SOX11: a potentially useful marker in surgical pathology: a systematic analysis of SOX11 expression in epithelial and non-epithelial tumours. Histopathology. 2019 Feb;74(3):391-405. doi: 10.1111/his.13757. Epub 2018 Dec 2. PMID: 30221780.


Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD

Recent Posts

See All

Case 76

A 80-year-old male with a large neck mass. What is the molecular findings in the most likely diagnosis? A: MDM2 B: RB1 loss C: TP53...

Case 75

A 77-year-old female with a large appendix mass. What's your diagnosis? A: Poorly differentiated carcinoma B: Invasive lobular carcinoma...

Case 74

A 55-year-old male presented with a 3.5 cm thyroid mass. Question 1: Which of the following best describes the tumor mutation burden...

Comments

bottom of page