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Case 43

A 56-year-old female with a 4.7 cm right breast mass, and here is the core biopsy:





1.What is the morphology impression? What is the IHC panel you would like to order?


IHC

  • ER, PR

  • CK5/6, calponin, SMMHC

  • AR

  • S100



Answer

  1. If this is a invasive carcinoma and the MUC4 is positive, what's the molecular change?

    A: BRCA1

    B: BRCA2

    C: FUS-CREB

    D: MED12

    E: MYB-NFIB

    F: ETV6-NTRK3


Answer

Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD


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