A 56-year-old female with a 4.7 cm right breast mass, and here is the core biopsy:





1.What is the morphology impression? What is the IHC panel you would like to order?
IHC
ER, PR
CK5/6, calponin, SMMHC
AR
S100
Answer
If this is a invasive carcinoma and the MUC4 is positive, what's the molecular change?
A: BRCA1
B: BRCA2
C: FUS-CREB
D: MED12
E: MYB-NFIB
F: ETV6-NTRK3
Answer
Case credit: UCSD Pathology
Author: Wangpan Jackson Shi, MD
Comments