A 50 year old female with a mass involving bladder, and rectum. Here is the section with bladder mucosa. She has a history of cervical cancer.





Assuming the p16 and GATA3 are negative, and the tumor showed nuclear positivity of the stain above, what's the diagnosis by morphology.
A: Urothelial carcinoma
B: Poorly differentiated carcinoma
C: Neuroendocrine carcinoma
D: Squamous cell carcinoma
Answer
Case credit: UCSD Pathology
Author: Wangpan Shi, MD
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