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Case 55

Feb 21

A 65-year-old male was found to have a 13 cm abdominal mass.






  1. What immunostains you would like to order?


IHC

  • Pan-keratin

  • S100

  • SMA

  • Desmin


  1. What is your diagnostic line for this tumor if MDM2 turned out to be positive?

    A: Well differentiated liposarcoma

    B: Low grade dedifferentiated liposarcoma

    C: Dedifferentiated liposarcoma

    D: Liposarcoma, see comment



Answer

Zhang H, Erickson-Johnson M, Wang X, Oliveira JL, Nascimento AG, Sim FH, Wenger DE, Zamolyi RQ, Pannain VL, Oliveira AM. Molecular testing for lipomatous tumors: critical analysis and test recommendations based on the analysis of 405 extremity-based tumors. Am J Surg Pathol. 2010 Sep;34(9):1304-11. doi: 10.1097/PAS.0b013e3181e92d0b. PMID: 20679883.


Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD


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