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Case 64

A 73-year-old female presented with a submandibular mass.





  1. Which translocation is most commonly found in MECs, leading to the expression of the CRTC1::MAML2 fusion gene?

    A. t(11;19)(q21;p13)

    B. t(11;15)(q21;q26)

    C. t(6;22)(p21;q12)

    D. t(19;11)(p13;q21)


Answer

  1. Which tumor grade in MECs typically exhibits negligible copy-number variation and few somatic mutations, such as TP53 and POU6F2?

A. High-grade MECs

B. Intermediate-grade MECs

C. Low-grade MECs

D. All tumor grades equally


Answer



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