Case 69

A 45-year-old female with a large lung mass measuring 12.5 cm.

1. If the cells observed that are positive for both EMA and TTF-1, negative for CD34, what's your diagnosis?

   A: Adenocarcinoma

   B: Solitary fibrous tumor

   C: Pecoma

   D: Sclerosing pneumocytoma

   E: Carcinoid tumor

Answer

2. Do you know the molecular findings that alway present in this diagnosis?

   A: ALK

   B: ATK-1

   C: B-catenin

   D: ESR1

   F: AKT-1

   
   

Answer

Reference: https://tumourclassification.iarc.who.int/chaptercontent/35/11

Case credit: https://qp.91360.com/27.html?lang=en

Author: Wangpan Jackson Shi, MD