A 30-year-old female with an ovarian mass.





What is the diagnosis by morphology?
A: Fibroma
B: Thecoma
C: Signet ring stromal tumor
D: Adult granulosa cell tumor
E: Sclerosing stromal tumor
Answer
What is the molecular change in this pure stromal tumor?
A: CTNNB1 mutation
B: FOXL2 mutation
C: DICER1 mutation
D: GLI2 rearrangment
F: PTEN mutation
Answer
Case credit: UCSD Pathology
Author: Wangpan Jackson Shi, MD
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