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Case 8

Updated: Jan 23

A 40-year-old female with a cervical mass presented with abnormal uterine bleeding. An endometrial biopsy as well as endocervical curettage were sent for pathology. Below is the EMB sample:






1.What is the diagnosis by morphology?

A: FIGO3 endometrioid carcinoma

B: Clear cell carcinoma

C: Endometrioid carcinoma with mucinous differentiation

D: Invasive stratified mucin producing carcinoma

E: Squamous cell carcinoma

F: Microgandular hyperplasia


Answer


  1. Here is the section from the ECC specimen:

A panel of immunostains showed that the tumor cells are diffusely positive for P16, negative for ER. What's the final diagnosis?

A: FIGO3 endometrioid carcinoma

B: Clear cell carcinoma

C: Endometrioid carcinoma with mucinous differentiation

D: Invasive stratified mucin producing carcinoma

E: Squamous cell carcinoma

F: Microgandular hyperplasia

Answer


Case credit: UCSD Pathology

Author: Wangpan Jackson Shi, MD


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